Wellcome Sanger Institute, Cambridge, U.K. Department of Public Health and Primary Care, The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, U.K. NHS Blood and Transplant, John Radcliffe Hospital, Oxford, U.K. Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, U.K. British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, U.K. British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, U.K. Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, U.K. Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX. Department of Haematology, University of Cambridge, Cambridge, U.K. National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, U.K. Department of Epidemiology, Johns Hopkins University, Baltimore, MD. Exeter Centre of Excellence for Diabetes Research, University of Exeter Medical School, Exeter, U.K.